Gentamicin vestibulotoxicity: detection and prevention

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/245515

Funding Status
Closed

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Funded Activity Summary

A powerful, life-saving and cheap antibiotic, gentamicin, has one potential serious permanent side-effect: loss of balance due to damage to the balance organs of the inner ears. Detected early, the inner ear damage can be reversed by stopping gentamicin. Until now there has been no way of monitoring inner ear balance at the bedside. We have now developed such a method and want to show that by monitoring inner ear balance of patients needing gentamicin we can detect damage at such an early stage that stopping the drug and using another instead will allow the balance organs to recover by themselves.

Funded Activity Details

Start Date: 01-01-2003

End Date: 01-01-2005

Funding Scheme: NHMRC Project Grants

Funding Amount: $205,500.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Neurology And Neuromuscular Diseases

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

ANTIBIOTIC THERAPY | BALANCE | CLINICAL TEST OF VESTIBULAR FUNCTION | CRITICAL CARE MEDICINE/ANTIBIOTIC USE/DECISION SUPPORT | DRUG TOXICITY | JUDICIOUS ANTIBIOTIC USE | OTOTOXICITY | VESTIBULAR DYSFUNCTION | VESTIBULAR FUNCTION

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