Mechanisms underlying short- and long-term plasticity at the mossy fibre -> CA3 synapse in the hippocampus

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/236801

Funding Status
Closed

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Funded Activity Summary

Synapses, the contacts between brain cells, are extremely plastic. They can become stronger and weaker depending on the activity they experience. The hippocampus, a structure in the brain, is known to be critical to the formation of conscious memories. The plastic nature of the synapse in this structure is thought to underlie learning and memory. Understanding the mechanisms that are responsible for the changes in synaptic strength in the hippocampus are therefore important to our understanding of learning and memory. This proposal describes a series of experiments that are designed to determine the mechanisms of plastic changes . We hope, that by understanding these mechanisms, we can start to understand how we learn and remember.

Funded Activity Details

Start Date: 01-01-2003

End Date: 01-01-2005

Funding Scheme: NHMRC Project Grants

Funding Amount: $272,750.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical parasitology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

LTP | alzheimers | calcium | epilepsy | hippocampus | kainate receptors | learning | memory | mossy fibre

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