Single nephron GFR and tubuloglomerular feedback before and after birth.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/222757

Funding Status
Closed

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Funded Activity Summary

In this project we want to study the forces responsible for the filtration of plasma by the kidney during development. This process is the first step in urine production. It is important to understand kidney function because abnormalities in kidney function can result in high blood pressure and chronic renal disease (requiring dialysis or transplant) in later life. It is reported that up to 40% of the population is salt sensitive i.e. their blood pressure increases when they are on a high salt diet. The cause of this salt sensitivity is unknown but we believe that it could be due to abnormalities in kidney function during fetal life. Alterations in function occuring during development can have life long effects through a process called fetal programming.

Funded Activity Details

Start Date: 01-01-2003

End Date: 01-01-2005

Funding Scheme: NHMRC Project Grants

Funding Amount: $402,428.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical molecular engineering of nucleic acids and proteins

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Fetal development | Fetal origins of adult disease | Fetal physiology | Hypertension | Kidney | Kidney disease | Micropuncture | Renal development & renal disease & hypertension as adults | Renal function

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