Development of site-specific predictive assay for periodontal disease progression using mass spectrometric &RT- PCR Anal

Funding Activity

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Funded Activity Summary

In this project new DNA-based technology will be developed to determine the numbers of specific bacteria in the dental plaque of patients. The project will also use new mass spectrometric analysis techniques for the determination of compounds in gingival crevicular fluid, an exudate from the gums. These two techniques will be used in a clinical trial to determine if periodontal (gum) disease progression can be predicted by changes in the numbers of bacteria or in the composition of gingival crevicular fluid. This could provide insight into the development of periodontal disease and lead to new preventive and treatment regimes.

Funded Activity Details

Start Date: 01-01-2002

End Date: 01-01-2006

Funding Scheme: NHMRC Strategic Awards

Funding Amount: $150,000.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical and Health Sciences

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

Clinical Trial | Mass Spectrometry | Microbial aetiology | Periodontitis | RT-PCR