Effects of oestrogen on mood, memory and quality of life of women aged 70 years or over

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/211976

Funding Status
Closed

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Funded Activity Summary

Oestrogen has a number of actions that extend well beyond the regulation of the reproductive cycle and sexual behaviour. The results of recent studies indicate that oestrogen may influence mood and a number of intellectual abilities such as memory and language. In addition, oestrogen replacement therapy seems to reduce the risk of Alzheimer's disease (the most frequent cause of dementia in Western societies) amongst postmenopausal women. The present study aims to: (1) investigate the association of depression and memory performance with physiological levels of oestrogen in women aged 70 years or over; and (2) investigate the evolution of depression and memory scores in old women treated with oestrogen replacement therapy as compared to placebo. The results of the present study may have important implications in the prevention and management of two of the most relevant mental health disorders of later life: depression and Alzheimer's disease.

Funded Activity Details

Start Date: 01-01-2002

End Date: 01-01-2004

Funding Scheme: NHMRC Project Grants

Funding Amount: $170,990.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Geriatrics And Gerontology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cognitive deficit in the elderly | cognitive impairment | cognitive outcome | depression | depressive symptoms | elderly | mental health | oestrogen | quality of life

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