Transcriptional regulation of the c-fms (CSF-1R) gene in macrophages.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/210273

Funding Status
Closed

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Funded Activity Summary

This project concerns the basic biology of large white blood cells called macrophages. Macrophages are required for the immediate defence against infection, wound repair and normal turnover of tissues, but they can also produce toxic products that cause illness, especially in inflammatory diseases and cancer. We are studying a gene that is normally only produced in macrophages, but appears abnormally in many cancer cells. Our aim is understand at a molecular level exactly how the gene is controlled, and why it appears in tumours.

Funded Activity Details

Start Date: 01-01-2002

End Date: 01-01-2004

Funding Scheme: NHMRC Project Grants

Funding Amount: $422,310.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Gene Expression

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

CSF-1 | cancer | differentiation | genetics | inflammation | macrophage | transcription

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