Coordination of withdrawal from the cell cycle by transcriptional repression

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/208908

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

Cancer is characterised by changes in several fundamental cellular processes including the failure of the cancer cells to stop growing in response to the body's normal stop signals.. When cells normally stop growing there is profound changes in the activity of many genes. This proposal aims to investigate how these changes in gene activity are brought about. We propose that a recently discovered family of genes called SWI-SNF work with two other families of genes (the Mad-family and Rb-family) to bring about the cessation of cell growth. If our proposal is proven it will open new avenues to evaluate the growth properties of human cancers and may lead to novel strategies to inhibit cell growth.

Funded Activity Details

Start Date: 01-01-2002

End Date: 01-01-2004

Funding Scheme: NHMRC Project Grants

Funding Amount: $271,650.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cell Development (Incl. Cell Division And Apoptosis)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Benign Disorders of Excessive Cell Proliferation. | Cancer | Cell Differentiation | Cell division | Growth Disorders | Transcription | Tumour Suppressor

Related Links