Iron overload mechanisms in dyserythropoietic anaemias and therapeutic targets at the ERFE gene locus

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/2005394

Funding Status
Status not available

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Funded Activity Summary

Iron overload causes organ dysfunction and morbidity for people who have red blood cell disorders such as thalassemia, or chronic transfusion requirements due to cancer or bone marrow failure. The manner in which a principal controlling compound, erythroferrone, influences iron metabolism is undefined. Our project will use molecular approaches to determine how the erythroferrone gene is involved in causing iron overload in red cell disorders and potentially open better management pathways.

Funded Activity Details

Start Date: 01-01-2020

End Date: End date not available

Funding Scheme: Postgraduate Scholarships

Funding Amount: $132,743.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

blood transfusion | erythropoiesis | iron absorption | iron overload