Improving microvascular dysfunction in falciparum malaria

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/2005187

Funding Status
Status not available

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Funded Activity Summary

Additional treatments are needed to reduce global malaria mortality. In hospitalised patients with falciparum malaria we will evaluate new methods of assessing blood vessel dysfunction in malaria. We will use these methods to conduct a trial of the safety and efficacy of sodium nitrite, a widely available drug with the potential to treat malaria by increasing nitric oxide and improving blood flow. Our results will inform the design of a larger study of sodium nitrite to treat severe malaria.

Funded Activity Details

Start Date: 01-01-2020

End Date: End date not available

Funding Scheme: Postgraduate Scholarships

Funding Amount: $132,743.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

endothelial dysfunction | malaria therapy | nitric oxide | plasmodium falciparum

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