Understanding how the E3 ubiquitin ligase Parkin dictates neuronal survival

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/2004446

Funding Status
Status not available

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Funded Activity Summary

Parkinson's disease is the fastest-growing neurodegenerative disorder, and the second most common neurodegenerative disease after Alzheimer's disease. The disease arises due to the loss of specific neurons in the brain that control motor function. We aim to understand what triggers these neurons to die and to resolve how inflammation promotes disease. This information will underpin the development of the first, and much needed, drugs that slow or stop Parkinson's disease progression.

Funded Activity Details

Start Date: 01-01-2020

End Date: End date not available

Funding Scheme: Ideas Grants

Funding Amount: $947,560.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

apoptosis of neurons | neurodegeneration | neuroinflammation | parkinson disease