The microenvironmental drivers of T cell regulation in metastatic breast cancer

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/2004253

Funding Status
Status not available

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Funded Activity Summary

COX2 inhibitors are drugs commonly used by cancer patients to relieve pain and inflammation. Using human breast cancer samples and mouse models of breast cancer, we show that pathways targeted by these drugs provide an immunological brake that prevents T cells being activated as strongly as they could be, and which has not been studied. This project is expected to yield important anti-cancer targets that could be used to develop a new class of cancer drugs.

Funded Activity Details

Start Date: 01-01-2020

End Date: End date not available

Funding Scheme: Ideas Grants

Funding Amount: $1,302,611.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

fibroblasts | lymph node | nonsteroidal antiinflammatory drugs (nsaids) | t cells

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