THE IMMUNOLOGICAL LEGACY OF OBESITY ON VIRAL PATHOGENESIS

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/2003959

Funding Status
Status not available

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Funded Activity Summary

Obesity is a key risk factor for severe viral infections. Our preliminary data suggest that in mice this susceptibility is not reduced by weight loss. In this grant we will investigate a) the mechanisms driving the legacy effect of obesity on antiviral immunity b) whether or not we can reverse this legacy effect by treatment with the drug MCC950 and c) the antiviral response of overweight children and adults who have and haven't recently lost weight.

Funded Activity Details

Start Date: 01-01-2020

End Date: 01-01-2020

Funding Scheme: Ideas Grants

Funding Amount: $652,275.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

influenza virus | innate immunity | overweight/obesity | viral infection

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