Targeting the NLRP3 inflammasome and interleukin-18 in hypertensive heart failure

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/2003752

Funding Status
Status not available

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Funded Activity Summary

Heart failure is a common complication of hypertension and a major cause of death and disability worldwide. This project will characterise a newly identified inflammatory pathway that we believe to be a major cause of the enlargement and scarring of the heart that accompanies hypertension. We will also trial drugs that block this inflammatory pathway to determine their suitability as future therapies for this devastating disease.

Funded Activity Details

Start Date: 01-01-2020

End Date: End date not available

Funding Scheme: Ideas Grants

Funding Amount: $1,241,115.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cardiac dysfunction | cardiac hypertrophy | hypertension | immunotherapy

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