Understanding novel viral host interactions that modulate innate immunity

Funding Activity

Website
https://www.nhmrc.gov.au/sites/default/files/documents/attachments/grant%20documents/2020_ideas_grants_recommended_for_funding_commencing_2021.pdf

Funding Status
Status not available

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Funded Activity Summary

Lethal viruses such as coronaviruses (MERS, SARS-CoV-1, SARS-CoV-2), Dengue, Zika, Hendra, and Nipah have developed effective mechanisms of replication by dampening the host immune system. Here we will examine how viruses carry out these immune evasion functions, and test antiviral drugs that can prevent these effects in a highly specific manner. If this idea can be proved, it will provide great promise for the development of new antivirals whilst minimising the toxic effects to the cell.

Funded Activity Details

Start Date: 01-01-2020

End Date: 01-01-2025

Funding Scheme: Ideas Grants

Funding Amount: $764,246.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

dengue | innate immunity | virology | x-ray crystallography

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