Analysis of the osteoclast methylome for characterisation of epigenetic mechanisms underlying metabolic bone disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/2003629

Funding Status
Status not available

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Funded Activity Summary

A large number of genetic variants have been identified that have a role in osteoporosis, however for many of these, the mechanism by which they influence the disease remains to be determined. This study will fill a critical knowledge gap by investigating the epigenetic control of gene expression in osteoclasts (bone resorbing cells). This research will generate a unique international resource that will provide foundation data to understand and treat this prevalent and debilitating bone disease.

Funded Activity Details

Start Date: 01-01-2020

End Date: End date not available

Funding Scheme: Ideas Grants

Funding Amount: $299,018.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

dna methylation | epigenetics | osteoclast | osteoporosis

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