Examining the role of extracellular myeloperoxidase in the pathogenesis, identification and treatment of high-risk unstable and ruptured atherosclerotic plaque

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/2002759

Funding Status
Status not available

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Funded Activity Summary

Vascular inflammation has emerged as a key driver and therapeutic target for stroke and heart attack. Existing diagnostic techniques and treatments do not target inflammation so that residual inflammatory risk remains. There is a need to identify patients with active inflammation who may benefit from treatment. Myeloperoxidase is an inflammatory enzyme abundant in plaque at risk of rupture and subsequent stroke or heart attack and presents as a potential diagnostic tool and therapeutic target.

Funded Activity Details

Start Date: 01-01-2020

End Date: End date not available

Funding Scheme: Postgraduate Scholarships

Funding Amount: $103,356.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

atherosclerosis | carotid artery disease | inflammation | vascular biology