Identifying the molecular basis of memory B cell function and human immunoglobulin E memory via Hyper Immunoglobulin E Syndromes

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/2002673

Funding Status
Status not available

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Funded Activity Summary

Memory B cells generate rapid and potent antibody responses to known threats. The molecular basis for this is unknown, but defects increase the risk of infection, autoimmunity, and allergy. Autoimmunity and allergy are often mediated by a poorly understood antibody subclass, immunoglobulin E (IgE). My project will use emerging single-cell technologies to reveal the molecular mechanisms of antibody memory and IgE regulation, enabling the design of superior vaccines and immunomodulatory therapy.

Funded Activity Details

Start Date: 01-01-2020

End Date: End date not available

Funding Scheme: Postgraduate Scholarships

Funding Amount: $96,009.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

humoral immunology | immunogenetics | immunoglobulin e (ige) | immunologic memory

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