Targeting complement C5a receptor 2 as a disease-modifying treatment for motor neuron disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/2000095

Funding Status
Status not available

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Funded Activity Summary

Motor neuron disease (MND) is a devasting terminal condition that has no effective treatment. We have identified a novel drug which inhibits an immune protein that can potentially treat MND. In this project we will test this drug in rodent models of MND, and validate its effectiveness in relevant MND immune cells. Ultimately, this project will identify a new potential drug for MND.

Funded Activity Details

Start Date: 01-01-2020

End Date: End date not available

Funding Scheme: Development Grants

Funding Amount: $636,329.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

antisense oligonucleotides | complement c5a | neuroinflammation | pre-clinical studies

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