Factors affecting the conductance of GABA(A) channels

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/179835

Funding Status
Closed

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Funded Activity Summary

GABA(A) receptors provide most of the inhibition in the brain. If they are blocked, animals suffer from seizures and die. They are the target for a wide variety of medically useful drugs such as anaesthetics, tranquillisers such as valium and anti-epleptic drugs. All these drugs boost their effectiveness and increase inhibition in the brain. Most of them were discovered by chance. In this project, we will find out more about these receptors. This will give us more information about how the brain works and also help in the search for better, more selective drugs.

Funded Activity Details

Start Date: 01-01-2002

End Date: 01-01-2004

Funding Scheme: NHMRC Project Grants

Funding Amount: $406,650.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical parasitology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Acute anxiety | Anaesthesia | Epilepsy | Ion channel biophysics | Receptor proteins | Synaptic inhibition

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