Immunoregulatory T cells and Tumour Immunity

Funded Activity Summary

Cancer is one of the leading causes of death in the industrialized world. While therapies to treat cancer have continued to improve one area that, in theory at least, shows great promise in the treatment of tumours is manipulating the immune system to effectively recognize and destroy cancerous lesions. Experiments in human and animal systems have clearly shown that the immune system has the potential to respond to tumour cells and trials of tumour vaccines are underway. It has recently become apparent that the immune responses to tumours may be inhibited by classes of regulatory immune cells. Eliminating these cells results in a more vigorous and effective anti-tumour response. This project will seek to discover the mechanisms of action of theses regulatory immune cells in order to devise more effective anti-cancer vaccines and therapies.

Funded Activity Details

Start Date: 01-01-2001

End Date: 01-01-2003

Funding Scheme: NHMRC Project Grants

Funding Amount: $212,036.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Clinical chemistry (incl. diagnostics)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Autoimmunity | Cancer | Cytotoxic T cells | Helper T cells | Immunoregulatory T cells | Solid tumours | Tumour immunity | mesothelioma

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