CHARACTERISATION OF A NOVEL REGULATOR OF PHOSPHOINOSITIDE 3-KINASE-MEDIATED CELL PROLIFERATION AND PLATELET SIGNALLING

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/143542

Funding Status
Closed

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Funded Activity Summary

Critical functions such as cell growth, cell death and metabolism, are tightly controlled by key proteins which respond to specific stimuli. Perturbation of this process may lead to uncontrolled growth and cancer. This project proposes to examine the potential of a novel protein (an enzyme) as a physiological regulator of cell growth. It is proposed that this enzyme may function as a brake in preventing the evolution of a cancerous state. We will also study the ability of the novel enzyme to influence other diverse functions, such as uptake of glucose, and blood clot initiation.

Funded Activity Details

Start Date: 01-01-2001

End Date: 01-01-2003

Funding Scheme: NHMRC Project Grants

Funding Amount: $500,091.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Oncology And Carcinogenesis

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

HAEMOSTASIS | METABOLIC DISORDERS | ONCOLOGY | PHOSPHOINOSITIDE 3-KINASE | PLATELET SIGNALLING AND AGGREGATION | PROLIFERATION AND APOPTOSIS | PROTEIN TRAFFICKING | TUMOUR SUPPRESSOR

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