ANTIPODES The Australian National Trial Investigating Post-Operative Deficit, Early extubation and Survival

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/140510

Funding Status
Closed

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Funded Activity Summary

Brain damage following cardiac surgery is an unfortunate but common complication occuring variously in 30-80% of patients. Although severe strokes are uncommon (<1%), more subtle effects such as forgetfulness or behaviour changes may persist and make daily living difficult. Many attempts have been made to identify the exact cause of the brain damage, but no answer has been forthcoming. Recently, the introduction of modern anaesthetic techniques, which allow patients to wake up quickly after the operation, have given strong indications that they may also cause less brain damage. We plan to test this aspect of modern anaesthesia, by comparing the results of tests for brain damage after anaesthesia that has been given by traditional methods and the recent method which allows patients to wake up quickly.

Funded Activity Details

Start Date: 01-01-2001

End Date: 01-01-2003

Funding Scheme: NHMRC Project Grants

Funding Amount: $370,509.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Clinical nutrition

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

anaesthesia and cognitive deficit | cardiac anaesthesia | cognitive deficit in the elderly | coronary artery disease | early extubation | postoperative cognitive deficit | randomised controlled trial

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