Analysis of the Hematopoietic Function of Endophilin and MASH Proteins

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/139064

Funding Status
Closed

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Funded Activity Summary

We want to understand more about the control of blood cell formation and the development of leukaemia. We have discovered one gene that is very important in both these processes. It is the most common genetic abnormality involved in causing human T-cell leukaemia and we have recently shown that it is absolutely required for the development of all blood cells within an animal. We wish to understand how a gene important in blood cell formation can also be important in causing leukaemia. To address this we will study a new molecule with which it partners, and two molecules via which it exerts its actions.

Funded Activity Details

Start Date: 01-01-2001

End Date: 01-01-2003

Funding Scheme: NHMRC Project Grants

Funding Amount: $408,055.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Haematology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Aplastic Anaemia | Developmental haemopoiesis | Gene targeting | Haemopoiesis | Haemopoietic stem cells | Leukaemia | Transcription factor | Transgenic animals

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