Contributions of intrinsic renal cells to inflammatory renal injury

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/124413

Funding Status
Closed

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Funded Activity Summary

These studies aim to improve our understanding of glomeruonephritis, the most common cause of kidney failure. They will study the interactions between circulating white blood cells (leukocytes) which originate from the bone marrow , and intrinsic kidney cells in the development of tis disease. Inflammation is the result of recruitment of bone marrow derived inflammatory cells and plasma proteins to a variety of stimuli. The subsequent injury represents the interaction between recruited cells and local cells within the target organ. Glomerulonephritis is an important human disease where both bone marrow derived inflammatory and local cells have the potential to contribute to kidney injury by production of signalling molecules called cytokines. This study will determine the contribution of specific cytokines produced by intrinsic renal cells towards the development of inflammatory kidney injury in GN.

Funded Activity Details

Start Date: 01-01-2000

End Date: 01-01-2000

Funding Scheme: NHMRC Project Grants

Funding Amount: $66,433.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nephrology And Urology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cytokine | glomerulonephritis | inflammation | intrinsic cell | kidney | macrophage | renal failure

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