Elucidating metabolic dysregulation in Alzheimer’s disease: Profiling the peripheral immune cell lipidome to unravel pathological mechanisms.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1197190

Funding Status
Active

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Funded Activity Summary

Both the immune system and lipid metabolism have been identified to be important in Alzheimer’s disease (AD). With the failures of all clinical trials attempting to treat AD, we seek to determine a way to both better diagnose individuals with AD and to identify people at increased risk. This project uses a novel profiling technique to characterise the lipid composition of immune cells to diagnose, predict risk, monitor the disease and to identify potential disease modifying therapeutic targets.

Funded Activity Details

Start Date: 05-12-2019

End Date: End date not available

Funding Scheme: Investigator Grants

Funding Amount: $645,205.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

blood lipid metabolism | disease modelling | lipid metabolism | mass spectrometry

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