Molecular diagnosis and therapy of autoimmune disease using translational and reverse translational approaches

Funding Activity

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Funded Activity Summary

We plan to translate our recent discoveries on human gene variants and molecules produced by immune cells (follicular T cells) into effective therapies for autoimmune diseases. This will involve understanding the mechanisms by which the genes and molecules regulate immune tolerance, stratifying patients with autoimmune disease using newly identified biomarkers, trialling existing biologicals according to affected molecular pathway, and taking novel targets through to commercialisation.

Funded Activity Details

Start Date: 05-12-2019

End Date: End date not available

Funding Scheme: Investigator Grants

Funding Amount: $2,331,372.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

autoimmunity | b cells | immunogenetics | t cells