Structural biology and therapeutic targeting of axon degeneration

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1196590

Funding Status
Status not available

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Funded Activity Summary

The molecular mechanisms underlying SARM1 (sterile alpha and TIR 1) function will be investigated, which will allow design of inhibitors of axon degeneration, which can be developed into therapeutic agents for neurodegenerative disease. Outcomes are not only anticipated to support excellence in basic research, but have potential of assisting health sectors and the economy, by reducing the burden of prevalent neurodegenerative diseases such as peripheral neuropathies and traumatic brain injury.

Funded Activity Details

Start Date: 01-01-2020

End Date: 01-01-2018

Funding Scheme: Investigator Grants

Funding Amount: $1,512,250.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

axonal degeneration | drug design | nicotinamide adenine dinucleotide (nad) | protein structure

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