Tailoring dendritic cell diversity to advance effective immunotherapies

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1196235

Funding Status
Status not available

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Funded Activity Summary

Dendritic cells (DCs) constitute the first line of defense against infection and cancer. To achieve this feat, DC have evolved into a sophisticated network of specialized subtypes, although how this diversification process occurs is yet to be fully clarified. We have uncovered a new molecule, termed DC-SCRIPT, which has a key role in establishing the DC network, specialization and function. This offers crucial new clues as to how to manipulate DCs to either boost or dampen the immune system.

Funded Activity Details

Start Date: 01-01-2020

End Date: End date not available

Funding Scheme: Investigator Grants

Funding Amount: $645,205.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

cytokines | dendritic cell lineages | differentiation | tumour immunotherapy

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