Targeting vitamin-reactive T cells for enhanced immunity

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1193745

Funding Status
Status not available

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Funded Activity Summary

A specialised set of T cells called mucosal-associated invariant T (MAIT) cells react against bacteria and yeast, and reside at mucosal sites where the body's immune defences are often breached, e.g. respiratory tract and intestinal mucosa. This study seeks to define the molecular signals driving the function of MAIT cells, particularly during infections. This information may lead to methods tailored to manipulating MAIT cells therapeutically.

Funded Activity Details

Start Date: 01-01-2020

End Date: End date not available

Funding Scheme: Investigator Grants

Funding Amount: $2,590,576.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cellular immunity | immunopathology | infection | t cell immunity