Antigen-specific regulatory T cells and HLA associations in autoimmune renal disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1150684

Funding Status
Closed

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Funded Activity Summary

Glomerulonephritis (GN), a common cause of kidney failure, usually results from an immune system attack on the kidneys. Current treatments suppress the whole immune system, making patients vulnerable to infection. We aim to harness the body’s protective immune cells (Tregs) as a potential GN treatment. Using mice genetically programmed to mimic a human GN, we will test if specifically targeted Tregs protect mice from disease. We will also test how they affect blood samples from humans with GN.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2021

Funding Scheme: Postgraduate Scholarships

Funding Amount: $128,224.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nephrology and Urology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

autoimmunity | glomerulonephritis | human leukocyte antigen (HLA) | kidney failure | regulatory T cells

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