Protective mechanisms of MAP kinase phosphatase 5 in adipose tissue fibrosis, hepatic steatosis and atherosclerosis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1149062

Funding Status
Closed

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Funded Activity Summary

Obesity and associated complications such as diabetes, non-alcoholic fatty liver disease and atherosclerosis are a serious health burden. Recently, we found that MKP5, a molecule that restricts intracellular signaling, plays a central role in preventing these diseases. This collaborative project will elucidate how precisely MKP5 acts and explore how this molecule can be targeted for the development of novel therapeutic strategies in prevention and treatment of human metabolic diseases.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2020

Funding Scheme: Targeted Calls

Funding Amount: $352,729.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Physiology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cardiovascular disease | diabetes | liver disease | metabolic syndrome | obesity

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