Bacterial metabolite mediated regulation of the immune and metabolic systems

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1148476

Funding Status
Closed

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Funded Activity Summary

The cellular and molecular events that underpin metabolic syndrome diseases, such as diabetes, fatty liver, etc are poorly understood. However recent advances provide new clues. First, the immune system is intimately connected to metabolism. Second, the gut microbiota, and its metabolites such as acetate and butyrate are also important. These metabolites induce epigenetic changes in cells. We will study how metabolites induce molecular changes epigenetically, and how this controls metabolism.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2020

Funding Scheme: Targeted Calls

Funding Amount: $303,374.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical and Health Sciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

dendritic cell lineages | epigenetics | inflammation | metabolic syndrome | metabolism

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