Understanding how the Helicobacter pylori pilin protein CagL promotes gastric cancer

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1148142

Funding Status
Closed

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Funded Activity Summary

The bacterium Helicobacter pylori is a major cause of gastric cancer and chronic gastritis. The bacterial protein CagL is a key disease-causing protein of H. pylori and potent stimulant of host immune responses. This study aims to understand how this virulent bacterial protein promotes cancer development, and to identify novel therapeutic targets and diagnostic markers for better management of gastric cancer and other severe chronic gastric diseases.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2021

Funding Scheme: Project Grants

Funding Amount: $677,177.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Microbiology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

bacterial pathogenesis | cancer biology | chronic inflammation | host/pathogen interaction | virulence factors

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