The Effects of Human Epilepsy Mutations on Synaptic GABA-A Receptors Studied by Localization-based Superresolution Microscopy

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1147600

Funding Status
Closed

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Funded Activity Summary

The genetic epilepsies are debilitating neurological disorders that are frequently associated with mutations in genes encoding neurotransmitter-gated receptors in the brain. The goal of this project is to understand mechanisms that cause changes in neuronal communication and lead to epilepsy on a single receptor level. This will lead to an improved understanding of the mechanisms of epileptogenesis and new insights into ways of treating different epilepsies.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2020

Funding Scheme: Project Grants

Funding Amount: $524,215.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Central Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

channelopathy | ion channels | neuroimaging | patch clamp | trafficking

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