Functional and molecular profiling of platelet hyperactivity in diabetes - uncovering dysregulated and targetable pathways for potential treatments

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1146025

Funding Status
Closed

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Funded Activity Summary

The major cause of death in diabetes is cardiovascular disease. Diabetic patients are more likely to have hardening of their arteries, and an increased propensity to form pathological blood clots. I propose to characterise platelet “hyperactivity” in diabetes both at a functional and molecular level. This unique approach aims to identify the underlying mechanism of platelet hyperactivity which may be targeted in future treatments.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2021

Funding Scheme: Early Career Fellowships

Funding Amount: $318,768.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

cardiovascular disease | diabetes mellitus | integrins | platelet function | thrombosis

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