Pharmacological development of a stable cytochrome P450-mediated omega-3 fatty acid epoxide analogue as a novel anti-metastatic agent

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1145424

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

Dietary ?-3 fatty acids decrease the risk of cancer metastasis. We have found that a certain ?-3 fatty acid metabolite inhibits tumour cell migration but is too unstable to be a useful drug. We have now prepared a stable version of this metabolite for in vivo use as a potential anti-metastatic drug. In this project we will define the mechanism of action of this novel agent and evaluate how it may be best used in patient treatments by testing in a range of in vivo animal models of metastasis.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2020

Funding Scheme: Project Grants

Funding Amount: $599,847.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Pharmacology and Pharmaceutical Sciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cancer chemotherapy | cell migration | cytochrome P450 | drug development | fatty acid metabolism

Related Links