Targeting the de novo serine synthesis pathway in macular disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1145121

Funding Status
Closed

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Funded Activity Summary

We have found a significant difference in de novo serine metabolism between the human primary Müller cells isolated from macular and peripheral retinas. We will study whether and how this difference contributes to redox homeostasis in these areas. The outcomes will help us to gain a better understanding of why the macula is more prone to develop disease than the peripheral retina.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2020

Funding Scheme: Project Grants

Funding Amount: $628,084.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Ophthalmology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Muller cell | macular disease | molecular biology | oxidative stress | retinal degeneration

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