The dual-edged sword of zinc as an innate immune antimicrobial weapon against uropathogenic E. coli

Funding Activity

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Funded Activity Summary

Infectious diseases are a major global health threat, and urinary tract infections (UTI) are one of the most common infectious diseases. Most UTI are caused by uropathogenic E. coli (UPEC). In order to cause infections, UPEC must be able to overcome our body’s first line of defence, the innate immune system. This project seeks to understand how our innate immune system uses zinc to combat bacterial infections, and how UPEC is able to defend against such responses in order to cause disease.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2020

Funding Scheme: Project Grants

Funding Amount: $784,428.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Innate Immunity

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Escherichia coli | bacterial pathogenesis | innate immunity | macrophage biology | urinary tract infection (UTI)