Molecular pathogenesis of mixed lineage leukaemia

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1144649

Funding Status
Closed

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Funded Activity Summary

Chromosomal translocations in the MLL gene results in aggressive leukaemias. Several drugs developed to target proteins that interact with the MLL fusion proteins are now being tested in the clinic. Despite this progress, our understanding of how the MLL fusion proteins cause leukaemia remains incomplete. In particular, it is unclear how the MLL fusion protein drives the development of leukaemia. In this project I will address these important issues with cell and molecular biology methods.

Funded Activity Details

Start Date: 01-01-2019

End Date: 01-01-2021

Funding Scheme: Project Grants

Funding Amount: $467,214.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Haematological Tumours

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

biochemistry | bioinformatics | epigenetics | leukaemia | molecular biology

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