A novel approach to identify the specific antibody characteristics important for protection from malaria in pregnant women

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1143946

Funding Status
Closed

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Funded Activity Summary

Antibody protects against malaria, but the specific characteristics of protective antibody are unknown. Pregnant women lack antibody to parasite protein called VAR2CSA, explaining their malaria susceptibility. Using samples from vaccine trials and clinical studies in pregnant women, and a ‘Systems Serology’ approach, we will determine which naturally-acquired or vaccine induced antibodies protect pregnant women from malaria, and how variation in VAR2CSA sequences affects this protection.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2021

Funding Scheme: Project Grants

Funding Amount: $1,011,223.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Parasitology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Plasmodium falciparum | antibody | malaria | malaria vaccine | serology

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