In vivo real-time tracking of “color-coded” supercharged Mesenchymal Stem Cells and T cells in allograft rejection

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1143655

Funding Status
Closed

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Funded Activity Summary

Growing specialized adult stem cells (MSC) in the presence of a unique immune signaling protein (IL-17) has generated a “supercharged” stem cell with superior abilities to dampen immune responses in cell and organ transplant patients. The use of these MSC in transplant patients may significantly reduce the dose of anti-rejection drugs required to prevent cell and organ rejection. By minimizing the dose of drugs, we aim to eliminate the risk of developing infections and cancer in these patients.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2022

Funding Scheme: Early Career Fellowships

Funding Amount: $408,768.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Transplantation Immunology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

adult stem cells | allogeneic transplantation | immunomodulation | translational research | type 1 diabetes mellitus (insulin-dependent diabetes mellitus)

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