A New Approach To Restoring Glucose Homeostasis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1143601

Funding Status
Closed

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Funded Activity Summary

We have discovered that activating a cell surface protein increases blood sugar levels in mice. This might occur in diabetes and liver disease. We plan to (1) learn which activators of this protein increase glucose; (2) understand how they affect glucose metabolism; (3) study new inhibitors of this protein for blocking increased glucose production; (4) test the potential therapeutic benefits of blocking this protein in mouse models of type 2 diabetes and non-alcoholic fatty liver disease.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2021

Funding Scheme: Project Grants

Funding Amount: $936,494.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Pharmaceutical Sciences

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

diabetes | glucose homeostasis | obesity | pharmacology | protease-activated receptors

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