Tumour-on-a-chip models for ex-vivo profiling of immune checkpoint blockades

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1143377

Funding Status
Closed

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Funded Activity Summary

The overall goal of this project is to build novel 3D biochips to culture primary human tumors with their immune cells, and to investigate patient specific responses to immune checkpoint blockade ex-vivo. Since there are currently no validated methodologies to study immunotherapy response in patient-derived cancer specimens, this proposal has the potential to provide a state-of-the art technology for the ‘personalization’ of immunotherapy.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2021

Funding Scheme: Career Development Fellowships

Funding Amount: $431,000.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biomedical Engineering not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cancer | cancer care | immunotherapy | targeted therapy | tissue engineering

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