Bioresponsive Porous Silicon for Site Specific Oral Delivery of Antibodies for the Treatment of Inflammatory Bowel Disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1143296

Funding Status
Closed

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Funded Activity Summary

This proposal aims to develop an oral antibody delivery system for treatment of inflammatory bowel disease (IBD) that affects 75000 Australians. The system will be based on porous silicon nanoparticles acting as a container to protect the antibodies, and bioresponsive coatings acting as gates to enable site specific protein delivery at the inflamed site of GI tract. The project not only holds promise for protein delivery for the treatment of IBD but other diseases like diabetes.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2021

Funding Scheme: Early Career Fellowships

Funding Amount: $318,768.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nanomedicine

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

antibody therapy | inflammatory bowel disease (IBD) | intestinal mucosa | nanotechnology | ulcerative colitis

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