Targeting dysfunctional mitochondria in macrophages to inhibit atherosclerosis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1142938

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

The major contributing cells to heart disease are macrophages. These cells scavenge cholesterol, keeping the blood vessels clean and limiting heart disease. The macrophages must process and donate the scavenged cholesterol onto HDL-cholesterol that carries them back to the liver for removal. This process requires the powerhouse of the cell, the mitochondria to be functional. We have discovered that process fails and have novel drugs to re-instate this process of cholesterol removal.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2021

Funding Scheme: Project Grants

Funding Amount: $1,009,796.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

atherosclerosis | inflammation | lipids | macrophages | mitochondria

Related Links