Stroke induced disturbances in glymphatic clearance: implications for brain repair?

Funding Activity

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Funded Activity Summary

We have made a remarkable discovery that the ability of the brain to clear waste proteins is significantly impaired after stroke. This may have important implications for development of dementia and milder changes in thinking late after stroke. We already have some clues regarding potential mechanisms. In this project we will further investigate these mechanisms and their effects on the brain and develop our understanding of potential ways to reverse the clearance problem to develop treatments.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2020

Funding Scheme: Project Grants

Funding Amount: $491,688.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

animal model | aquaporin | cerebral infarction | neurodegeneration | stroke