Targeting redox homeostasis to prevent Mycobacterium tuberculosis persistence

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1142699

Funding Status
Closed

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Funded Activity Summary

Tuberculosis is now the leading cause of death from infectious disease worldwide. This reflects the ability of its causative agent to persist, leading to failure of antibiotic treatment and development of drug resistance. In this project, we propose to overcome this by inhibiting a unique metabolic pathway that is activated when the pathogen enters its persistent state. We will use a cutting-edge combination of techniques to develop this pathway for next-generation therapies.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2020

Funding Scheme: Project Grants

Funding Amount: $396,025.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Enzymes

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Mycobacterium tuberculosis | antibiotic resistance | biosynthesis | metabolism | persistence

Related Links