Epithelial Drivers of Neutrophil Plasticity in Early Cystic Fibrosis Lung Disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1142505

Funding Status
Closed

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Funded Activity Summary

Why airway inflammation becomes chronic so early in life for people with cystic fibrosis (CF) is unclear. This project will use the latest techniques to characterise immune cells found in airways of infants with CF and model in the laboratory how immune cells react to the CF airway. We will challenge CF airway cells with different bugs that can infect the lung, then see if the responses by CF airway cells can change the normal response of immune cells, triggering chronic disease.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2021

Funding Scheme: Project Grants

Funding Amount: $849,462.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Paediatrics

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

airway inflammation | cystic fibrosis | epithelial biology | innate immunity | neutrophils

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