Targeting RCAN1 to treat type 2 diabetes and obesity

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1142403

Funding Status
Closed

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Funded Activity Summary

Obesity and impaired insulin secretion are significant contributors to Type 2 diabetes. In this project we demonstrate that a protein called RCAN1 contributes to both fat mass and insulin secretion and that this contribution is exacerbated in obesity and in Type 2 diabetes. We will identify how RCAN1 controls these major metabolic pathways with outcomes including the development of new therapeutics for obesity and Type 2 diabetes.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2020

Funding Scheme: Project Grants

Funding Amount: $814,468.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Endocrinology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

adipocytes | insulin secretion | obesity | therapeutic agents | type 2 diabetes mellitus (non-insulin dependent diabetes mellitus)

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