The regulatory role of Clec12A in antigen presentation and inflammatory disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1142358

Funding Status
Closed

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Funded Activity Summary

The immune system maintains a balance between initiating immune responses to infections and suppressing immune responses in health. We have identified, on the surface of specialised immune cells, a protein that is critical for regulating immune responses and dampening down inflammation. This proposal aims to determine how this protein functions in health and under inflammatory conditions, and to develop approaches based on its molecular interactions to reduce inflammatory disease.

Funded Activity Details

Start Date: 01-01-2018

End Date: 01-01-2022

Funding Scheme: Project Grants

Funding Amount: $1,381,077.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Innate Immunity

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

antigen presenting cells | cell surface receptor | dendritic cell | macrophage biology | receptor regulation

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